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During the Covid-19 pandemic a key role is played by vaccination to combat the virus. There are many possible policies for prioritizing vaccines, and different criteria for optimization: minimize death, time to herd immunity, functioning of the health system. Using an age-structured population compartmental finite-dimensional optimal control model, our results suggest that the eldest to youngest vaccination policy is optimal to minimize deaths. Our model includes the possible infection of vaccinated populations. We apply our model to real-life data from the US Census for New Jersey and Florida, which have a significantly different population structure. We also provide various estimates of the number of lives saved by optimizing the vaccine schedule and compared to no vaccination. 

Abstract We consider the task of recovering a pair of vectors from a set of rank one bilinear measurements, possibly corrupted by noise. Most notably, the problem of robust blind deconvolution can be modeled in this way. We consider a natural nonsmooth formulation of the rank one bilinear sensing problem and show that its moduli of weak convexity, sharpness and Lipschitz continuity are all dimension independent, under favorable statistical assumptions. This phenomenon persists even when up to half of the measurements are corrupted by noise. Consequently, standard algorithms, such as the subgradient and prox-linear methods, converge at a rapid dimension-independent rate when initialized within a constant relative error of the solution. We complete the paper with a new initialization strategy, complementing the local search algorithms. The initialization procedure is both provably efficient and robust to outlying measurements. Numerical experiments, on both simulated and real data, illustrate the developed theory and methods.